A sprain is the stretching or tearing of _____________ and other tissues at a joint.

A sprain specifically involves the stretching or tearing of ligaments, which are tough, flexible bands of connective tissue that connect bones at a joint. Ligaments play a crucial role in stabilizing joints and preventing excessive movement that could lead to injury. When a joint is twisted or impacted in a way that its normal range of motion is exceeded, ligaments can become overstretched or torn, resulting in a sprain.

The other choices relate to tissues associated with joints and movement but are not correct in the context of a sprain. Cartilaginous tissues are involved in cushioning joints but are not the primary structures affected in a sprain. Tendons connect muscles to bones and can be involved in other types of injuries, like strains, rather than sprains. Osteopathic refers to a branch of medicine focused on the treatment of the whole person rather than a specific tissue type, so it does not pertain to the definition of a sprain. Thus, ligaments are the key tissues affected in these kinds of injuries.